이비인후과 영역의 창상 치유에 2-Octylcyanoacrylate(Dermabond^®)의 이용

Background and Objectives: Cyanoacrylate-based adhesives are topical glues that bond to the outermost layer of skin to form a seal over the apposed edges of laceration or incision. 2-Octylcyanoacrylate is a long carbon chain cyanoacrylate derivatives that is stronger and more pliable than its shorter chain derivatives. This study was performed to evaluate the effectiveness of the tissue adhesiveness of 2-Octylcyanoacrylate with suture for the wound closure of otorhinolaryngologic field. Materials and Methods: Thirty-six patients who underwent preauricular fistulectomy, thyroidectomy, mastoidectomy between March and June 2002 were enrolled: the 2-Octylcyanoacrylate group (n=18) and the suture group (n=18). The length of time for repair was recorded. The incisions were evaluated with visual analog scale (VAS) and Hollander wound evaluation scale (HWES) after 12 weeks. Results: 2-Octylcyanoacrylate provided faster skin closure, and there were no differences in complications between the two groups. Results of VAS and HWES revealed equivalent cosmetic results in both group. Conclusion: Application of 2-Octylcyanoacrylate may be an effective method of skin closure in otorhinolaryngologic field. (J Clinical Otolaryngol 2003;14:244-248)