Journal of Clinical Otolaryngology Head and Neck Surgery
The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery
임상
비강 및 상악동의 도립 유두종에서 유래된 편평세포암 1례 (유세포계 측검 색 의 추적 관찰)
최충식1, 이흥만1, 최건1, 황순재1
A Case of Squamous Cell Carcinoma Arising from Inverted Papilloma in Nose and Paranasal Sinus—Follow-up with Flow Cytometry
Choong Sik Choi1, Heung Man Lee1, Geon Choi1, Soon Jae Hwang1
1고려대학교 의과대학 이비인후一두경부외과학교실
1Department of Otolaryngology—Head and Neck Surgery, Korea University, College of Medicine, Seoul, Korea
© Copyright 1995 The Busan, Ulsan, Gyeoungnam Branch of Korean Society of Otolaryngology-Head and Neck Surgery. This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Published Online: May 31, 2020
ABSTRACT
Inverted papilloma has been known their specific characteristics of local aggressiveness, recurrence after prompt treatment and malignant transformation. The malignant transformation rate was variable from 2% to 53%. But there was no clinical prognostic indicator in their malignant potency. DNA flow cytometry may appreciate biologic behavior of the tumor. Clinicopathologic aspect of the tumor and the degree of aneuploidy is helpful to understand the malignant potency. Recently, the authors experienced the one case of maxillary squamous cell carcinoma arising from inverted papilloma, previously operated 4 times and reported with DNA flow cytometric results. It is suggested that DNA flow cytometry may be prognostic indicator in malignant transformation of inverted papilloma.
Keywords: Inverted papilloma; Squamous cell carcinoma; Flow cytometry
